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1

Is low fertility really a problem? Population aging, dependency, and consumption

Lee, R., Mason, A., Lee, R., Mason, A., Amporfu, E., An, C.-B., Bixby, L. R., Bravo, J., Bucheli, M., Chen, Q., Comelatto, P., Coy, D., d'Albis, H., Donehower, G., Dramani, L., Furnkranz-Prskawetz, A.

Journal:

Year:

2014

Language:

english

File:

PDF, 415 KB

english, 2014

2

The Cancer Genome Atlas Pan-Cancer analysis project

Chang, Kyle, Creighton, Chad J, Davis, Caleb, Donehower, Lawrence, Drummond, Jennifer, Wheeler, David, Ally, Adrian, Balasundaram, Miruna, Birol, Inanc, Butterfield, Yaron S N, Chu, Andy, Chuah, Eric,

Journal:

Nature Genetics

Year:

2013

Language:

english

File:

PDF, 608 KB

english, 2013

3

How does suppression of IGF-1 signaling by DNA damage affect aging and longevity?

George Hinkal, Lawrence A. Donehower

Journal:

Mechanisms of Ageing and Development

Year:

2008

Language:

english

File:

PDF, 510 KB

english, 2008

4

Taxol: A Novel Investigational Antimicrotubule Agent

Rowinsky, E. K., Cazenave, L. A., Donehower, R. C.

Journal:

JNCI Journal of the National Cancer Institute

Year:

1990

Language:

english

File:

PDF, 3.46 MB

english, 1990

5

55K isoform of CDK9 associates with Ku70 and is involved in DNA repair

Hongbing Liu, Christine H. Herrmann, Karen Chiang, Tzu-Ling Sung, Sung-Hwan Moon, Lawrence A. Donehower, Andrew P. Rice

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 722 KB

english, 2010

6

Rilotumumab in combination with epirubicin, cisplatin, and capecitabine as first-line treatment for gastric or oesophagogastric junction adenocarcinoma: an open-label, dose de-escalation phase 1b study and a double-blind, randomised phase 2 study

Iveson, Timothy, Donehower, Ross C, Davidenko, Irina, Tjulandin, Sergey, Deptala, Andrzej, Harrison, Mark, Nirni, Somanath, Lakshmaiah, Kuntegowdanahalli, Thomas, Anne, Jiang, Yizhou, Zhu, Min, Tang,

Journal:

The Lancet Oncology

Year:

2014

Language:

english

File:

PDF, 339 KB

english, 2014

7

[ACM Press the 20th ACM SIGKDD international conference - New York, New York, USA (2014.08.24-2014.08.27)] Proceedings of the 20th ACM SIGKDD international conference on Knowledge discovery and data mining - KDD '14 - Automated hypothesis generation based on mining scientific literature

Spangler, Scott, Myers, Jeffrey N., Stanoi, Ioana, Kato, Linda, Lelescu, Ana, Labrie, Jacques J., Parikh, Neha, Lisewski, Andreas Martin, Donehower, Lawrence, Chen, Ying, Lichtarge, Olivier, Wilkins,

Year:

2014

Language:

english

File:

PDF, 2.22 MB

english, 2014

8

Trans-ancestry mutational landscape of hepatocellular carcinoma genomes

Totoki, Yasushi, Tatsuno, Kenji, Covington, Kyle R, Ueda, Hiroki, Creighton, Chad J, Kato, Mamoru, Tsuji, Shingo, Donehower, Lawrence A, Slagle, Betty L, Nakamura, Hiromi, Yamamoto, Shogo, Shinbrot, E

Journal:

Nature Genetics

Year:

2014

Language:

english

File:

PDF, 1.08 MB

english, 2014

9

Widespread and tissue specific age-related DNA methylation changes in mice

Maegawa, S., Hinkal, G., Kim, H. S., Shen, L., Zhang, L., Zhang, J., Zhang, N., Liang, S., Donehower, L. A., Issa, J.-P. J.

Journal:

Genome Research

Year:

2010

Language:

english

File:

PDF, 1.17 MB

english, 2010

10

Taxol: Twenty Years Later, the Story Unfolds

Rowinsky, E. K., Donehower, R. C.

Journal:

JNCI Journal of the National Cancer Institute

Year:

1991

Language:

english

File:

PDF, 469 KB

english, 1991

11

Exercise Effects on Tumorigenesis in a p53-Deficient Mouse Model of Breast Cancer

COLBERT, LISA H., WESTERLIND, KIM C., PERKINS, SUSAN N., HAINES, DIANA C., BERRIGAN, DAVID, DONEHOWER, LAWRENCE A., FUCHS-YOUNG, ROBIN, HURSTING, STEPHEN D.

Journal:

Medicine & Science in Sports & Exercise

Year:

2009

Language:

english

File:

PDF, 317 KB

english, 2009

12

Contemporary Outcome Research and Programming Guidelines for Asperger Syndrome and High-Functioning Autism

Tsatsanis, Katherine D., Foley, Christine, Donehower, Claire

Journal:

Topics in Language Disorders

Year:

2004

Language:

english

File:

PDF, 97 KB

english, 2004

13

21st Century Change Drivers: Considerations for Constructing Transformative Models of Special Education Teacher Development

Rock, M. L., Spooner, F., Nagro, S., Vasquez, E., Dunn, C., Leko, M., Luckner, J., Bausch, M., Donehower, C., Jones, J. L.

Journal:

Teacher Education and Special Education The Journal of the Teacher Education Division of the Council for Exceptional Children

Year:

2016

Language:

english

File:

PDF, 362 KB

english, 2016

14

Teacher professional learning using simulation: a Delphi study

Donehower Paul, Claire, Bukaty, Caitlyn A., Dieker, Lisa

Journal:

Teacher Development

Year:

2019

Language:

english

File:

PDF, 1.28 MB

english, 2019

15

Best Practices in Family Life Education Programming for Midlife and Older Adults

Benson, Jacquelyn J., Donehower, Allison K.

Journal:

Family Relations

Year:

2020

File:

PDF, 162 KB

2020

16

Long term follow-up of women treated with 16-week, dose-intensive adjuvant chemotherapy for high risk breast carcinoma

Bahar Mikhak, Marianna Zahurak, Martin D. Abeloff, John H. Fetting, Nancy E. Davidson, Ross C. Donehower, William Waterfield, M. John Kennedy

Journal:

Year:

1999

Language:

english

File:

PDF, 84 KB

english, 1999

17

Increased tumor cell proliferation in murine tumors with decreasing dosage of wild-type p53

Stuart D. Tyner, Jene Choi, Rodolfo Laucirica, Richard J. Ford, Lawrence A. Donehower

Journal:

Molecular Carcinogenesis

Year:

1999

Language:

english

File:

PDF, 832 KB

english, 1999

18

Taxol toxicity. Epithelial necrosis in the gastrointestinal tract associated with polymerized microtubule accumulation and mitotic arrest

Ralph H. Hruban, John H. Yardley, Ross C. Donehower, John K. Boitnott

Journal:

Year:

1989

Language:

english

File:

PDF, 825 KB

english, 1989

19

Effect of Intragastric Application of N-Methylnitrosourea in p53 Knockout Mice

Hiroko Ohgaki, Masakatsu Fukuda, Yasuo Tohma, Huatao Huang, George Stoica, Masae Tatematsu, Lawrence A. Donehower

Journal:

Molecular Carcinogenesis

Year:

2000

Language:

english

File:

PDF, 269 KB

english, 2000

20

Cooperation between Ha-ras and fos or transforming growth factor α overcomes a paradoxic tumor-inhibitory effect of p53 loss in transgenic mouse epidermis

Xiao-Jing Wang, David A. Greenhalgh, Lawrence A. Donehower, Dennis R. Roop

Journal:

Molecular Carcinogenesis

Year:

2000

Language:

english

File:

PDF, 245 KB

english, 2000

21

Peripheral neuropathy from taxol and cisplatin combination chemotherapy: Clinical and electrophysiological studies

Dr. Vinay Chaudhry, Eric K. Rowinsky, Susan E. Sartorius, Ross C. Donehower, David R. Cornblath

Journal:

Annals of Neurology

Year:

1994

Language:

english

File:

PDF, 711 KB

english, 1994

22

Environmental carcinogens and p53 tumor-suppressor gene interactions in a transgenic mouse model for mammary carcinogenesis

Daniel Medina, Robert Ullrich, Raymond Meyn, Roger Wiseman, Larry Donehower

Journal:

Environmental and Molecular Mutagenesis

Year:

2002

Language:

english

File:

PDF, 96 KB

english, 2002

23

Suppression of thymic lymphomas and increased nonthymic lymphomagenesis in Trp53-deficient mice lacking inducible nitric oxide synthase gene

Masayuki Tatemichi, Hiroshi Tazawa, Mitsuharu Masuda, Mohammad Saleem, Sayori Wada, Lawrence A. Donehower, Hiroko Ohgaki, Hiroshi Ohshima

Journal:

International Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 1.42 MB

english, 2004

24

Does p53 affect organismal aging?

Lawrence A. Donehower

Journal:

Journal of Cellular Physiology

Year:

2002

Language:

english

File:

PDF, 135 KB

english, 2002

25

Augmented cancer resistance and DNA damage response phenotypes in PPM1D null mice

Bonnie Nannenga, Xiongbin Lu, Melissa Dumble, Marc Van Maanen, Thuy-Ai Nguyen, Richard Sutton, T. Rajendra Kumar, Lawrence A. Donehower

Journal:

Molecular Carcinogenesis

Year:

2006

Language:

english

File:

PDF, 382 KB

english, 2006

26

Infrequent p53 mutations in 7,12-dimethylbenz[a]anthracene–induced mammary tumors in BALB/c and p53 hemizygous mice

D. Joseph Jerry, Janet S. Butel, Lawrence A. Donehower, Emily J. Paulson, Charles Cochran, Roger W. Wiseman, Daniel Medina

Journal:

Molecular Carcinogenesis

Year:

1994

Language:

english

File:

PDF, 804 KB

english, 1994

27

Effects of genetic background on tumorigenesis in p53-deficient mice

Lawrence A. Donehower, Michele Harvey, Hannes Vogel, Mark J. McArthur, Charles A. Montgomery Jr., Sang H. Park, Timothy Thompson, Richard J. Ford, Allan Bradley

Journal:

Molecular Carcinogenesis

Year:

1995

Language:

english

File:

PDF, 566 KB

english, 1995

28

Phase II study of N-methylformamide, spirogermanium, and 4-demethoxydaunorubicin in the treatment of non-small cell lung cancer (EST 3583): An Eastern cooperative oncology group study

David S. Ettinger, Dianne M. Finkelstein, Ross C. Donehower, Alex Y. C. Chang, Michael Green, Ronald Blum, Richard G. Hahn, John C. Ruckdeschel

Journal:

Pediatric Blood & Cancer

Year:

1989

Language:

english

File:

PDF, 407 KB

english, 1989

29

Adjuvant Concurrent Chemoradiation for Adenocarcinoma of the Distal Common Bile Duct

Michael A. Hughes, Deborah A. Frassica, Charles J. Yeo, Taylor S. Riall, Keith D. Lillemoe, John L. Cameron, Ross C. Donehower, Daniel A. Laheru, Ralph H. Hruban, Ross A. Abrams

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2007

Language:

english

File:

PDF, 251 KB

english, 2007

30

A Phase I Tolerability and Pharmacokinetic Study of Adjuvant Erlotinib (E) and Capecitabine (Cap) with Concurrent Radiation (RT) in Resected Pancreatic Cancer (PanCa)

W. Ma, J.M. Herman, D. Laheru, W. Messersmith, A. Jimeno, M. Rudek, Y. Khan, A. Howard, R. Donehower, M. Hidalgo

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2008

Language:

english

File:

PDF, 39 KB

english, 2008

31

Validation and implementation of a liquid chromatography/tandem mass spectrometry assay to quantitate ON 01910.Na, a mitotic progression modulator, in human plasma

Jing Li, Ming Zhao, Antonio Jimeno, Ping He, M.V. Ramana Reddy, Manuel Hidalgo, Ross C. Donehower, Michelle A. Rudek

Journal:

Journal of Chromatography B

Year:

2007

Language:

english

File:

PDF, 213 KB

english, 2007

32

Intensified adjuvant combined modality therapy for resected periampullary adenocarcinoma: acceptable toxicity and suggestion of improved 1-year disease-free survival

Anuradha Chakravarthy, Ross A Abrams, Charles J Yeo, Larry T Korman, Ross C Donehower, Ralph H Hruban, Marianna L Zahurek, Louise B Grochow, Seamus O’Reilly, Herbert Hurwitz, Elizabeth M Jaffee, Keith

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2000

Language:

english

File:

PDF, 136 KB

english, 2000

33

Intensified adjuvant therapy for periampullary (pancreatic, nonpancreatic) adenocarcinoma using irradiation, 5FU, mitomycin C, leucovorin and dipyridamole (J9625)-update results

R.A Abrams, L.T Korman, C.J Yeo, E Jaffee, A Chakravarthy, M.L Zahurak, T Sohn, R.H Hruban, R.C Donehower, K.D Lillemoe, J.L Cameron

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2000

Language:

english

File:

PDF, 266 KB

english, 2000

34

207 A phase II study of intensified adjuvant therapy for resected pancreatic and other periampullary adenocarcinoma using radiation, 5Fu, leucovorin, dipyridamole and mitomycin-C

A. Chakravarthy, C.J. Yeo, R.C. Donehower, L.B. Grochow, S. O'Reilly, M.L. Zahurek, R.H. Hruban, H.I. Hurwitz, E. Jaffee, L. Korman, K.D. Lillemoe, J.L. Cameron, R.A. Abrams

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1999

Language:

english

File:

PDF, 264 KB

english, 1999

35

Insights into stem cells and aging provided by a P53 mutant mouse

L.A. Donehower, C. Gatza, G. Hinkal, L. Moore, N. Parikh, S. Chambers, F. Kittrell, J. Xu, A. Lee, D. Medina, M. Goodell

Journal:

Critical Reviews in Oncology/Hematology

Year:

2008

Language:

english

File:

PDF, 48 KB

english, 2008

36

Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models

Tamara Terzian, Melissa Dumble, Farinaz Arbab, Christina Thaller, Lawrence A Donehower, Guillermina Lozano, Monica J Justice, Dennis R Roop, Neil F Box

Journal:

The Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 684 KB

english, 2011

37

The Clinical Development of Paclitaxel: A Successful Collaboration of Academia, Industry and the National Cancer Institute

Dr. Ross C. Donehower

Journal:

Year:

1996

Language:

english

File:

PDF, 23 KB

english, 1996

38

Phase II Studies

M. John Kennedy, Ross C. Donehower, Louise B. Grochow, David S. Ettinger, John H. Fetting, Martin D. Abeloff

Journal:

Investigational New Drugs

Year:

1990

Language:

english

File:

PDF, 451 KB

english, 1990

39

Assessment of N-methylformamide (NMF) administered orally on a three times weekly schedule: a phase I study

Eric K. Rowinsky, Louise B. Grochow, Alexander Hantel, David S. Ettinger, Barbara L. Vito, Ross C. Donehower

Journal:

Investigational New Drugs

Year:

1989

Language:

english

File:

PDF, 717 KB

english, 1989

40

Evaluation of weekly escalating doses of dichloromethotrexate in patients with hepatocellular carcinoma and other solid tumors

William J. Tester, Ross C. Donehower, Joyce L. Eddy, Charles E. Myers, Daniel C. Ihde

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1982

Language:

english

File:

PDF, 525 KB

english, 1982

41

A phase I trial of trimetrexate glucuronate (NSC 352122) given every 3 weeks: clinical pharmacology and pharmacodynamics

Louise B. Grochow, Dennis A. Noe, David S. Ettinger, Ross C. Donehower

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1989

Language:

english

File:

PDF, 694 KB

english, 1989

42

Basic fibroblast growth factor and fibroblast growth factor receptor I are implicated in the growth of human astrocytomas

Richard S. Morrison, Fumio Yamaguchi, Hideyuki Saya, Janet M. Bruner, Alan M. Yahanda, Lawrence A. Donehower, Mitchel Berger

Journal:

Journal of Neuro-Oncology

Year:

1994

Language:

english

File:

PDF, 947 KB

english, 1994

43

p53 in embryonic development: maintaining a fine balance

J. Choi, L. A. Donehower

Journal:

Cellular and Molecular Life Sciences

Year:

1999

Language:

english

File:

PDF, 162 KB

english, 1999

44

Phase I and pharmacokinetic study of UCN-01 in combination with irinotecan in patients with solid tumors

Antonio Jimeno, Michelle A. Rudek, Thomas Purcell, Daniel A. Laheru, Wells A. Messersmith, Janet Dancey, Michael A. Carducci, Sharyn D. Baker, Manuel Hidalgo, Ross C. Donehower

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2008

Language:

english

File:

PDF, 438 KB

english, 2008

45

Phase I trial of weekly trabectedin (ET-743) and gemcitabine in patients with advanced solid tumors

Wells A. Messersmith, Antonio Jimeno, David Ettinger, Dan Laheru, Julie Brahmer, Dina Lansey, Yasmin Khan, Ross C. Donehower, Yusri Elsayed, Peter Zannikos, Manuel Hidalgo

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2008

Language:

english

File:

PDF, 316 KB

english, 2008

46

A multicenter analysis of GTX chemotherapy in patients with locally advanced and metastatic pancreatic adenocarcinoma

Ana De Jesus-Acosta, George R. Oliver, Amanda Blackford, Katharine Kinsman, Edna I. Flores, Lalan S. Wilfong, Lei Zheng, Ross C. Donehower, David Cosgrove, Daniel Laheru, Dung T. Le, Ki Chung, Luis A.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2012

Language:

english

File:

PDF, 361 KB

english, 2012

47

The effects of food and divided dosing on the bioavailability of oral vinorelbine

E. K. Rowinsky, V. Sol Lucas, A.-L. Y. Hsieh, William A. Wargin, John A. Hohneker, Barbara Lubejko, Susan E. Sartorius, Ross C. Donehower

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1996

Language:

english

File:

PDF, 605 KB

english, 1996

48

Phase I trial of the matrix metalloproteinase inhibitor BAY12-9566 in patients with advanced solid tumors

Elisabeth I. Heath, Seamus O'Reilly, Rachel Humphrey, Pavur Sundaresan, Ross C. Donehower, Susan Sartorius, John M. Kennedy, Deborah K. Armstrong, Michael A. Carducci, Mel J. Sorensen, Karen Kumor, Se

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2001

Language:

english

File:

PDF, 90 KB

english, 2001

49

Bioavailablility of penclomedine and systemic exposure to 4-O-demethylpenclomedine in patients receiving oral and intravenous penclomedine

Seamus O'Reilly, Neil R. Hartman, Katherine M. Bowling, Eric K. Rowinsky, Ross C. Donehower, Jerry Collins, John M. Strong

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2001

Language:

english

File:

PDF, 119 KB

english, 2001

50

High susceptibility of nullizygous p53 knockout mice to colorectal tumor induction by 1,2-dimethylhydrazine

Hiroki Sakai, Tetsuya Tsukamoto, Masami Yamamoto, Norimitsu Shirai, Takeshi Iidaka, Akihiro Hirata, Tokuma Yanai, Toshiaki Masegi, Lawrence A. Donehower, Masae Tatematsu

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2003

Language:

english

File:

PDF, 299 KB

english, 2003

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